NO !
I have only used magnum primers in 223/556 with ball powders. 7.62X39R with ball powders. 6.8spc with ball powders.
Experimented with 308win a lot with ball and stick powders.Military and BR primers seem to work best(MHO).CCI 34 is my 1st choice, Win WLR 2nd,CCI 200 on plinker loads with 150gr projectiles . Rem 9 1/2 primers flattened the bases on my brass.
The Rem 9 1/2M over pressured the brass.Fed 210M on FGGM clone loads.
I use Win WLRM on the 270WSM and 300WSM loads and won't change primers just powders and projectiles.