You'll find that your final zero will be a little different, when you're looking at total turret travel, and it won't be 14.5 mils up and down exactly, but that's because of the scope centerline and barrel centerline (height over bore) coming in pretty close to 2.5". You'll see that the total travel up and down will favor drop, for distance.
On my hand-made brass and handloads, I'm pushing the Hornady 147 ELD-M at 2650fps with 43.0gr of RL-22 powder and CCI-200 primers. Nothing wild about the load. That keeps me supersonic to 1500 yards, and I'm 17.2 mils of drop at that distance. With your scope, you can easily run the gun out to it's supersonic range and still work it - dial what you can, and the reticle will allow you to hold the rest, based on that reticle design. Zero worries. It's gonna work. Once this beast is all together and broken in, I'll send you some of my ammo to try out.