I was just coming in here to state exactly that. 22LR is a weird little round, when you're trying to get it out there a ways. Supersonics hit the transonic shake, and do really strange things. If you can KEEP then supersonic the whole way to the target, they would do great. If you start out subsonic, or very close to sub (Mini-Mags are great), you won't have a hard time because they don't go through that shake.
We're talking about a projectile that has a G1 BC of 0.172... for the 40 grainers... It's no distance wizard all by itself, ya gotta work to get them out there. Really hard...
We had a 248 yard target at the last match I went to, and I got it. It was between 9 and 10 mils of dial to get it, though. In all honesty, I was shooting expensive stuff that my rifle loves, the SK Long Range Match ammo, 40gr.
However, when I was doing ammo testing, I'd already settle on the CCI Standard velocity because of how well it grouped through that rifle at the 50 yard zero. And, I know it hasn't let me down in the past. Then... A "buddy" walks up and hands be a box of the SK LR Match... It was just a little bit better, in terms of 50 yard groups and performance. Speeds were very close, both sub.
FWIW, on CCI, Standard Velocity is identical to MiniMag in performance, with the difference being the projectile coating. MiniMags are copper washed, Standards are just lead. That's why I preferred them in the Appleseeds - SVs are cheaper than MiniMags. Sounds crazy, but that's what it boiled down to.