I asked this question back when 300BO was still in its infancy. I was warned that mags and feed ramps don't like RN cartridges. Seeing the start of the SRC 25-45, that is all RN, I'm thinking the argument could be reexamined. You may have to experiment with COAL.
We had a member here, long ago, who was loading SMK Flat Bottom 126gr and getting 2,600fps.... I believe it was @Jgun but I haven't heard from him in years.